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phenotyper automated home cages model 3000  (Noldus Information Technology)

 
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    Noldus Information Technology phenotyper automated home cages model 3000
    Serial reversal learning with food reward in <t>PhenoTyper</t> cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.
    Phenotyper Automated Home Cages Model 3000, supplied by Noldus Information Technology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/phenotyper+automated+home+cages+model+3000/phenotyper+model+3000/pmc11911635-391-0-6
    Average 90 stars, based on 1 article reviews
    phenotyper automated home cages model 3000 - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "The behavioural consequences of dystrophinopathy"

    Article Title: The behavioural consequences of dystrophinopathy

    Journal: Disease Models & Mechanisms

    doi: 10.1242/dmm.052047

    Serial reversal learning with food reward in PhenoTyper cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.
    Figure Legend Snippet: Serial reversal learning with food reward in PhenoTyper cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.

    Techniques Used:

    Spontaneous behavior in the PhenoTyper cages: activity-based behavior. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) Mdx52 mice showed a higher habituation index during the dark phase compared to WT, mdx 5cv and DMD-null mice ( P< 0.001, P= 0.025 and P <0.001, respectively). (B) Mean activity duration during the dark phase was lower in DMD-null mice than in WT and mdx 5cv mice ( P= 0.002 and P< 0.001, respectively). (C) In DMD-null mice, activity in anticipation of the dark phase was less changed than in WT mice ( P =0.004). (D) DMD-null mice showed less change in activity in response to the start of the dark phase than WTs ( P= 0.023). (E) Mdx52 mice showed a higher increase in activity in anticipation of the start of the light phase than WTs ( P= 0.032). (F) Mdx52 mice showed a lower decrease in activity change in response to the start of the light phase than WT and mdx 5cv mice ( P= 0.037 and P< 0.001, respectively). DMD-null mice also showed less of a decrease in activity than mdx 5cv mice ( P< 0.001). * P< 0.05, ** P< 0.01, *** P <0.001 (one-way ANOVA with post-hoc Tukey).
    Figure Legend Snippet: Spontaneous behavior in the PhenoTyper cages: activity-based behavior. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) Mdx52 mice showed a higher habituation index during the dark phase compared to WT, mdx 5cv and DMD-null mice ( P< 0.001, P= 0.025 and P <0.001, respectively). (B) Mean activity duration during the dark phase was lower in DMD-null mice than in WT and mdx 5cv mice ( P= 0.002 and P< 0.001, respectively). (C) In DMD-null mice, activity in anticipation of the dark phase was less changed than in WT mice ( P =0.004). (D) DMD-null mice showed less change in activity in response to the start of the dark phase than WTs ( P= 0.023). (E) Mdx52 mice showed a higher increase in activity in anticipation of the start of the light phase than WTs ( P= 0.032). (F) Mdx52 mice showed a lower decrease in activity change in response to the start of the light phase than WT and mdx 5cv mice ( P= 0.037 and P< 0.001, respectively). DMD-null mice also showed less of a decrease in activity than mdx 5cv mice ( P< 0.001). * P< 0.05, ** P< 0.01, *** P <0.001 (one-way ANOVA with post-hoc Tukey).

    Techniques Used: Activity Assay

    Spontaneous behavior in the PhenoTyper cages: sheltering behavior, movement and arrest. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) The long shelter visit threshold was increased in mdx 5cv mice compared to that in WT and DMD-null mice ( P< 0.001 and P =0.007, respectively). (B) Both mdx52 and DMD-null mice showed a lower cumulative duration of shelter visits above the long shelter visit threshold compared to that in WTs ( P< 0.001 and P= 0.009, respectively). (C) The long movement threshold was lower in DMD-null mice than in WT, mdx 5v and mdx52 mice ( P< 0.001, P< 0.001 and P= 0.027, respectively). (D) DMD-null mice had a lower duration of arrests above the threshold than WT and mdx 5cv mice ( P= 0.014 and P= 0.009, respectively). * P< 0.05, ** P <0.01, *** P <0.001 (we refer the reader to for an overview of the statistical tests performed).
    Figure Legend Snippet: Spontaneous behavior in the PhenoTyper cages: sheltering behavior, movement and arrest. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) The long shelter visit threshold was increased in mdx 5cv mice compared to that in WT and DMD-null mice ( P< 0.001 and P =0.007, respectively). (B) Both mdx52 and DMD-null mice showed a lower cumulative duration of shelter visits above the long shelter visit threshold compared to that in WTs ( P< 0.001 and P= 0.009, respectively). (C) The long movement threshold was lower in DMD-null mice than in WT, mdx 5v and mdx52 mice ( P< 0.001, P< 0.001 and P= 0.027, respectively). (D) DMD-null mice had a lower duration of arrests above the threshold than WT and mdx 5cv mice ( P= 0.014 and P= 0.009, respectively). * P< 0.05, ** P <0.01, *** P <0.001 (we refer the reader to for an overview of the statistical tests performed).

    Techniques Used:

    Related Articles

    Activity Assay:

    Article Title: The behavioural consequences of dystrophinopathy
    Article Snippet: At 14 weeks of age, mice were housed in PhenoTyper automated home cages (model 3000, Noldus Information Technology, Wageningen, The Netherlands), in which spontaneous behavior, discrimination learning and reversal learning were also assessed ( ).

    Article Title: The behavioural consequences of dystrophinopathy
    Article Snippet: PhenoTyper automated home cages (model 3000, Noldus Information Technology) consist of transparent Perspex walls (30×30×35 cm) and opaque Perspex floors and an infra-red camera in the top unit.



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    Serial reversal learning with food reward in <t>PhenoTyper</t> cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.
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    Serial reversal learning with food reward in <t>PhenoTyper</t> cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.
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    Image Search Results


    Serial reversal learning with food reward in PhenoTyper cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.

    Journal: Disease Models & Mechanisms

    Article Title: The behavioural consequences of dystrophinopathy

    doi: 10.1242/dmm.052047

    Figure Lengend Snippet: Serial reversal learning with food reward in PhenoTyper cages. Mdx 5cv ( n =9-10), mdx52 ( n =14), DMD-null ( n =10-15) and WT ( n =32-33). (A) Discrimination learning (left target). Both mdx 5cv and mdx52 mice showed steeper learning curves than those of WTs ( P< 0.001 and P= 0.011, respectively) and DMD-null mice ( P< 0.001 and P= 0.018, respectively). (B) Reversal day 1 (right target). Mdx 5cv mice showed decreased learning compared to WTs ( P =0.017). (C) Reversal day 2 (left target). Mdx52 mice showed increased performance compared to WTs and mdx 5cv mice ( P< 0.001 and P= 0.013, respectively). (D) Reversal day 3 (middle target). Mdx52 mice showed increased learning compared to WTs ( P= 0.018). (E) Reversal day 4 (right target). No differences were found between groups. (F) Reversal day 5 (left target). No differences were found between groups. All graphs were cut off at n= 3 for visual purposes. Cartoons were created in BioRender by Verhaeg, M. (2025). https://BioRender.com/e60i623 . This figure was sublicensed under CC-BY 4.0 terms.

    Article Snippet: PhenoTyper automated home cages (model 3000, Noldus Information Technology) consist of transparent Perspex walls (30×30×35 cm) and opaque Perspex floors and an infra-red camera in the top unit.

    Techniques:

    Spontaneous behavior in the PhenoTyper cages: activity-based behavior. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) Mdx52 mice showed a higher habituation index during the dark phase compared to WT, mdx 5cv and DMD-null mice ( P< 0.001, P= 0.025 and P <0.001, respectively). (B) Mean activity duration during the dark phase was lower in DMD-null mice than in WT and mdx 5cv mice ( P= 0.002 and P< 0.001, respectively). (C) In DMD-null mice, activity in anticipation of the dark phase was less changed than in WT mice ( P =0.004). (D) DMD-null mice showed less change in activity in response to the start of the dark phase than WTs ( P= 0.023). (E) Mdx52 mice showed a higher increase in activity in anticipation of the start of the light phase than WTs ( P= 0.032). (F) Mdx52 mice showed a lower decrease in activity change in response to the start of the light phase than WT and mdx 5cv mice ( P= 0.037 and P< 0.001, respectively). DMD-null mice also showed less of a decrease in activity than mdx 5cv mice ( P< 0.001). * P< 0.05, ** P< 0.01, *** P <0.001 (one-way ANOVA with post-hoc Tukey).

    Journal: Disease Models & Mechanisms

    Article Title: The behavioural consequences of dystrophinopathy

    doi: 10.1242/dmm.052047

    Figure Lengend Snippet: Spontaneous behavior in the PhenoTyper cages: activity-based behavior. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) Mdx52 mice showed a higher habituation index during the dark phase compared to WT, mdx 5cv and DMD-null mice ( P< 0.001, P= 0.025 and P <0.001, respectively). (B) Mean activity duration during the dark phase was lower in DMD-null mice than in WT and mdx 5cv mice ( P= 0.002 and P< 0.001, respectively). (C) In DMD-null mice, activity in anticipation of the dark phase was less changed than in WT mice ( P =0.004). (D) DMD-null mice showed less change in activity in response to the start of the dark phase than WTs ( P= 0.023). (E) Mdx52 mice showed a higher increase in activity in anticipation of the start of the light phase than WTs ( P= 0.032). (F) Mdx52 mice showed a lower decrease in activity change in response to the start of the light phase than WT and mdx 5cv mice ( P= 0.037 and P< 0.001, respectively). DMD-null mice also showed less of a decrease in activity than mdx 5cv mice ( P< 0.001). * P< 0.05, ** P< 0.01, *** P <0.001 (one-way ANOVA with post-hoc Tukey).

    Article Snippet: PhenoTyper automated home cages (model 3000, Noldus Information Technology) consist of transparent Perspex walls (30×30×35 cm) and opaque Perspex floors and an infra-red camera in the top unit.

    Techniques: Activity Assay

    Spontaneous behavior in the PhenoTyper cages: sheltering behavior, movement and arrest. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) The long shelter visit threshold was increased in mdx 5cv mice compared to that in WT and DMD-null mice ( P< 0.001 and P =0.007, respectively). (B) Both mdx52 and DMD-null mice showed a lower cumulative duration of shelter visits above the long shelter visit threshold compared to that in WTs ( P< 0.001 and P= 0.009, respectively). (C) The long movement threshold was lower in DMD-null mice than in WT, mdx 5v and mdx52 mice ( P< 0.001, P< 0.001 and P= 0.027, respectively). (D) DMD-null mice had a lower duration of arrests above the threshold than WT and mdx 5cv mice ( P= 0.014 and P= 0.009, respectively). * P< 0.05, ** P <0.01, *** P <0.001 (we refer the reader to for an overview of the statistical tests performed).

    Journal: Disease Models & Mechanisms

    Article Title: The behavioural consequences of dystrophinopathy

    doi: 10.1242/dmm.052047

    Figure Lengend Snippet: Spontaneous behavior in the PhenoTyper cages: sheltering behavior, movement and arrest. Mdx 5cv ( n =14), mdx52 ( n =14), DMD-null ( n =16) and WT ( n =33). (A) The long shelter visit threshold was increased in mdx 5cv mice compared to that in WT and DMD-null mice ( P< 0.001 and P =0.007, respectively). (B) Both mdx52 and DMD-null mice showed a lower cumulative duration of shelter visits above the long shelter visit threshold compared to that in WTs ( P< 0.001 and P= 0.009, respectively). (C) The long movement threshold was lower in DMD-null mice than in WT, mdx 5v and mdx52 mice ( P< 0.001, P< 0.001 and P= 0.027, respectively). (D) DMD-null mice had a lower duration of arrests above the threshold than WT and mdx 5cv mice ( P= 0.014 and P= 0.009, respectively). * P< 0.05, ** P <0.01, *** P <0.001 (we refer the reader to for an overview of the statistical tests performed).

    Article Snippet: PhenoTyper automated home cages (model 3000, Noldus Information Technology) consist of transparent Perspex walls (30×30×35 cm) and opaque Perspex floors and an infra-red camera in the top unit.

    Techniques: